Yes and the evidence behind that answer is about as solid as it gets. Creatine is one of the most researched sports supplements. Across multiple trials in a 2024 meta-analysis, and across decades of broader creatine research, no clinically meaningful adverse events have been recorded in healthy adults.
The kidney-damage concern that has shadowed creatine since the nineties has never been substantiated by a large-scale human trial and a 2025 meta-analysis in BMC Nephrology put it plainly: while creatine raises serum creatinine, that's a metabolic byproduct, not a distress signal, glomerular filtration rate, the actual measure of how your kidneys are functioning, remains completely unaffected.
As for hair loss, a 2025 randomised controlled trial the first ever designed specifically to test this found no significant differences in DHT levels, hair density, or follicular count between creatine users and placebo.
The myth, at last, has nowhere left to hide.
That said, no supplement exists in a vacuum and creatine is no exception to the most sensible rule in wellness: know your own body first. While the evidence strongly supports its safety in healthy adults, anyone with pre-existing kidney disease, liver conditions, or a personal or family history of metabolic disorders should consult their doctor before beginning supplementation. The same applies if you are pregnant, breastfeeding, or currently taking prescribed medication. Creatine may interact with certain drugs, including nephrotoxic agents and diuretics, and the overlap deserves a conversation with a medical professional. If at any point during use you notice anything unexpected or out of the ordinary, stop and seek guidance.
This is not a caveat born of fear, it is the standard of care that every informed consumer deserves to extend to themselves. The science is reassuring. Your individual context is something only your doctor can read.